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OCR: ical lety of Hypopituitarism occurs frequency in cli ed by the endocrine practice and causes a wide va r. When symptoms and signs which are influenc aetiology and rate of onset of the disorde gnosis may hypopituitarism is slow in onset, the dis tuitarism be delayed, often for many years. Hypop al processes may be associated either with pathologic ose that that destroy the pituitary itself or with th fere with destroy the hypothalamus and thus inte e pituitary the hypothalamic hormone control of th Ical Although symptoms may be caused by 1 gland. ry or pressure effects in patients with a pituit e of parapituitary tumour, the clinical pictur itary hypopituitarism results chiefly from pit hormone deficiency,